Gusimbuza igice cy'ifu y'amafi n'ifu ya soya (SBM) nk'uburyo burambye kandi bunoze byasuzumwe mu moko menshi y'ubworozi bw'amafi yibandwaho ku bucuruzi, harimo n'udusimba two mu mazi meza (rainbow trout) (Oncorhynchus mykiss). Ariko, soya n'ibindi bimera birimo saponins nyinshi n'ibindi bintu birwanya intungamubiri bitera indwara ya subacute enteritis yo mu mara menshi muri aya mafi. Iyi ndwara irangwa no kwiyongera kw'imyororokere mu mara, kubyimba, no kutagira imiterere myiza bigatuma habaho kugabanuka k'ubushobozi bwo kurya no gukura nabi.

Mu mirire y’amafi yo mu bwoko bwa Rainbow trout, harimo na SBM irenga 20% by’indyo byagaragaye ko bitera soya-enteritis, bigashyira urwego rw’umubiri ku rwego rushobora gusimbuzwa indyo isanzwe yo mu mazi. Ubushakashatsi bwakozwe mbere bwasuzumye uburyo butandukanye bwo kurwanya iyi ndwara yo mu mara, harimo gukoresha mikorobe zo mu mara, gutunganya ibintu kugira ngo bikureho ibintu birwanya imirire, hamwe n’inyongera zirwanya antioxidant na probiotic. Uburyo bumwe butarasuzumwa ni ugushyira trimethylamine oxide (TMAO) mu biryo by’amafi yo mu mazi. TMAO ni umuti urinda indwara ku isi yose, ukusanyirizwa mu moko menshi nk’umuti utuma poroteyine n’uturemangingo bitazangiza membrane. Aha, turagerageza ubushobozi bwa TMAO bwo kongera ubushobozi bwo guhagarara kw’amafi no guhagarika ikimenyetso cya HSP70 gitera ububabare bityo tukarwanya soya-enteritis bigatuma ibiryo birushaho kuba byiza, kugumana no gukura mu mazi yo mu bwoko bwa Rainbow trout yo mu mazi meza. Byongeye kandi, turasuzuma niba ibishongeshwa mu mafi yo mu mazi, isoko ikungahaye kuri TMAO, bishobora gukoreshwa nk'uburyo bw'ubukungu bwo gutanga iyi nyongera, bigatuma ikoreshwa ku rwego rw'ubucuruzi.

Inyama zo mu bwoko bwa rainbow trout (Troutlodge Inc.) zashyizwe mu bubiko bufite uburemere bwa mbere bwa 40 g na n = 15 kuri buri tangi mu matangi atatu yo kuvura. Amatangi yagaburiwe imwe mu mafunguro atandatu yateguwe ku ntungamubiri zishobora kugogorwa itanga 40% bya poroteyine zishobora kugogorwa, 15% by'ibinure bidafite ifu, kandi yujuje ingano ikwiye ya aside amine. Indyo yari irimo ifu y'amafi 40 igenzurwa (% by'indyo yumye), SBM 40, SBM 40 + TMAO 3 g kg^-1, SBM 40 + TMAO 10 g kg^-1, SBM 40 + TMAO 30 g kg^-1, na SBM 40 + 10% by'ibishongeshwa by'amafi. Ibigega byagaburirwaga kabiri ku munsi kugeza bihaze mu gihe cy'ibyumweru 12 kandi hakorwa isesengura ry'amafi, hafi, histological na molekile.

Ibisubizo by'ubu bushakashatsi bizaganirwaho ndetse n'akamaro ko gushyiramo TMAO kugira ngo habeho ikoreshwa ryinshi ry'ibikomoka kuri soya byo muri Amerika mu biryo byo mu mazi bya salmon.