Gukoresha Ingeniyeri Yongeyeho ibiryo bishya-Glycerol Monolaurate mu bworozi bw'amafi

Mu myaka yashize, glyceride ya MCFA, nkubwoko bushya bwinyongera bwibiryo, yitabiriwe cyane kubera imikorere ya antibacterial nyinshi ningaruka nziza kubuzima bwo munda.Glycerol monolaurate (GML) ni intungamubiri ya MCFA monoester ibaho mumata yonsa namavuta ya cocout. FDA yemeje ko muri rusange ifatwa nk’umutekano iyo ikoreshejwe mu kigero cya 10 kugeza 2000mg / kg mu bicuruzwa bitandukanye. Usibye ingaruka za antibacterial na antiviral, ifite kandi emulisitiya.

Glycerol Monolaurate（URUBANZANo：142-18-7）

 Izina：Glycerol Monolaurate

Irindi zina：Monolaurin cyangwa GML

 Formula：C₁₅H₃₀O₄

uburemere bwa molekile：274.21

gukemura：Gushonga buhoro mumazina glycerol,gushonga muri methanol, Ethano

Kugaragara：Umweru cyangwa umuhondo ukomeye

GML ifite ubushobozi bwo kuguma mu nzira yigifu igihe kirekire no kunoza amara, bivuze ko GML ishobora kugira ingaruka ku buryo butaziguye mikorobe yo mu nda, ifasha umubiri gusarura intungamubiri zidashobora kwinjizwa kandi amaherezo bikazamura ubushobozi bwumubiri bwo gukuramo ingufu.

Kugeza ubu, ingaruka ziteza imbere no gukingira indwara ya monoglyceride mu nkoko zakozweho ubushakashatsi bwimbitse kugira ngo umusaruro w’amagi ube mwiza, ibiryo bigaburirwa, ubwiza bw’amagi n’agaciro k’intungamubiri z’inkoko. Byongeye kandi, GML ifite kandi ingaruka ziterambere ryubuzima kimwe nibikorwa bikomeye byo kurwanya inflammatory na antibacterial.

Ingaruka zo kugaburira monoglyceride ya laurate (GML) kumikorere yo gukura, imisemburo yimyunyungugu, ibigize umubiri hamwe nigisubizo kidasanzwe cyumudugudu wa Litopenaeus vannamei

2. Igishishwa cyakoreshejwe mubushakashatsi cyagaburiwe ibiryo bine bitandukanye, hamwe 0, 350, 700 na 1050mg / kg GML yongewe kubiryo. Ubushakashatsi bumaze iminsi 60.

Ibisubizo byubushakashatsi byerekana ko GML 700 na 1050 mg / kg bitezimbere cyane imikorere yiterambere, lipase yo munda hamwe nibikorwa bya protease, mugihe hiyongereyeho GML 1050 mg / kg mumirire byongera serumu lipide na lipide sisitemu.

Ibikorwa bya lipase yo munda na protease byerekanaga ko bigenda byiyongera hamwe n’imihindagurikire y’urwego rwa GML, kandi amatsinda ya GML mu matsinda ya dose ya 700 na 1050 mg / kg yari hejuru cyane ugereranije nitsinda rishinzwe kugenzura (P <0.05). Hagati aho, inzego zitandukanye za GML nta ngaruka nini zagize ku bikorwa bya enzymes zo mu gifu muri hepatopancreas.

Byongeye kandi, iyo GML yongewe kumirire yibirindiro bya 350 na 700mg / kg, byongera ubudahangarwa bwa shrimp mugutezimbere antioxydeant na antibacterial.

Ubushobozi bwa GML nkeya nkinyongeramusaruro yo kunoza imikurire, ibikorwa bya enzyme igogora hamwe nubudahangarwa budasanzwe bwa shrimp yera. Nk’uko ubushakashatsi bwakozwe bubigaragaza, kubera ibikorwa byiyongereye bya lipase yo mu nda na protease, ingano y’inyongera ya 700 na 1050 mg / kg GML yazamuye imikorere y’imikurire y’urusenda rwera ruva muri Amerika yepfo.