Fomate ya potasiyumu, inyongeramusaruro ya mbere idakoresha imiti yica udukoko yemejwe n'Umuryango w'Ubumwe bw'u Burayi mu 2001 ikemezwa na Minisiteri y'Ubuhinzi y'Ubushinwa mu 2005, imaze imyaka irenga 10 ikora gahunda y'ubugenzuzi, kandi inyandiko nyinshi z'ubushakashatsi haba mu gihugu no mu mahanga zavuze ingaruka zayo ku byiciro bitandukanye by'imikurire y'ingurube.

Necrotizing enteritis ni indwara y’inkoko ku isi iterwa na bagiteri za gram-positive (Clostridium perfringens), izongera impfu z’inkoko kandi ikagabanya imikorere y’inkoko mu buryo butari ubwa muganga. Ibi byombi byangiza imibereho myiza y’amatungo kandi bigateza igihombo gikomeye mu bukungu bw’inkoko. Mu musaruro nyawo, antibiyotike zikunze kongerwa mu biryo kugira ngo hirindwe ko havuka necrotizing enteritis. Ariko, gusaba kubuza antibiyotike mu biryo birimo kwiyongera, kandi hakenewe ubundi buryo bwo gusimbuza ingaruka zo gukumira antibiyotike. Ubushakashatsi bwagaragaje ko kongera aside organic cyangwa umunyu wazo mu mirire bishobora kugabanya ingano ya Clostridium perfringens, bityo bikagabanya igabanuka rya necrotizing enteritis. Potasiyumu formate irahinduka aside formic na potassium formate mu mara. Bitewe n’ubushobozi bwo guhuza ubushyuhe, aside formic imwe yinjira mu mara burundu. Iri gerageza ryakoresheje inkoko yanduye necrotizing enteritis nk'icyitegererezo cy’ubushakashatsi kugira ngo harebwe ingaruka zafomate ya potasiyumuku mikurire yayo, mikorobe zo mu mara, n'ingano y'aside irike y'uruhererekane rugufi.

1. Ingaruka zaPotasiyumu Diformateku mikurire y'inkoko z'inkoko zanduye indwara ya Necrotizing Enteritis.

Ibisubizo by'igerageza byagaragaje ko formate ya potasiyumu nta ngaruka nini yagize ku mikurire y'inkoko z'inkoko, haba cyangwa hatabayeho kwandura indwara ya enteritis, ibi bikaba bihuye n'ibyavuye mu bushakashatsi bwa Hernandez et al. (2006). Byagaragaye ko ingano imwe ya formate ya kalisiyumu nta ngaruka nini yagize ku kwiyongera k'ibiro bya buri munsi n'ibiryo by'inkoko z'inkoko, ariko iyo kongeramo formate ya kalisiyumu igera kuri 15 g/kg, byagabanyije cyane imikurire y'inkoko z'inkoko (Patten na Waldroup, 1988). Ariko, Selle et al. (2004) basanze kongeramo 6 g/kg ya formate ya potasiyumu mu ndyo byongera cyane kwiyongera kw'ibiro n'ibiryo by'inkoko z'inkoko ku minsi 16-35. Ubu hari raporo nke z'ubushakashatsi ku ruhare rwa aside organic mu gukumira kwandura kwa enteritis. Iri gerageza ryagaragaje ko kongeramo 4 g/kg ya potasiyumu mu ndyo byagabanyije cyane impfu z'inkoko z'inkoko, ariko nta sano n'ingaruka byagize hagati yo kugabanya impfu n'ingano ya formate ya potasiyumu yongewemo.

2. Ingaruka zaPotasiyumu Diformateku mikorobe ziri mu ngingo n'ingingo z'inkoko z'inkoko zandujwe n'indwara yo mu nda

Kongeramo 45mg/kg ya bacitracin zinc mu biryo byagabanyije impfu z'inkoko zanduye indwara ya necrotizing enteritis, kandi icyarimwe bigabanya ingano ya Clostridium perfringens muri jejunum, ibi bikaba byarahuye n'ibyavuye mu bushakashatsi bwa Kocher et al. (2004). Nta ngaruka nini zo kongeramo potasiyumu diformate ku bipimo bya Clostridium perfringens muri jejunum y'inkoko zanduye necrotizing enteritis mu gihe cy'iminsi 15. Walsh et al. (2004) basanze indyo irimo aside nyinshi zigira ingaruka mbi kuri aside organic, bityo, aside nyinshi y'indyo irimo poroteyine nyinshi ishobora kugabanya ingaruka zo gukumira potassium formate kuri necrotizing enteritis. Iri gerageza ryanagaragaje ko potassium formate yongera ingano ya lactobacilli mu nda y'inkoko 35d z'inkoko, ibi bikaba bidahuye n'ibyavumbuwe na Knarreborg et al. (2002) muri vitro ko potassium formate igabanya gukura kwa lactobacilli mu nda y'ingurube.

3.Ingaruka za potasiyumu 3-dimethylformate ku pH y'inyama n'ibinure bito mu nkoko z'inkoko zanduye indwara ya enteritis.

Ingaruka mbi za aside organic ziterwa na bagiteri zigaragara cyane cyane mu gice cyo hejuru cy'inzira y'igogora. Ibisubizo by'ubu bushakashatsi byagaragaje ko potasiyumu dicarboxylate yongera aside formike muri duodenum mu minsi 15 na jejunum mu minsi 35. Mroz (2005) yasanze hari ibintu byinshi bigira ingaruka ku mikorere ya aside organic, nko pH y'ibiryo, buffering/acidity, no kuringaniza electrolyte mu mirire. Aside nke n'agaciro ka electrolyte nyinshi mu mirire bishobora gutuma formate ya potasiyumu itandukana na aside formike na potassium formate. Kubwibyo, urwego rukwiye rw'aside na electrolyte iringaniza mu mirire rushobora kongera imikorere y'imikurire y'inkoko zo mu bwoko bwa potasiyumu na potassium formate ndetse n'ingaruka zayo zo gukumira enteritis itera indwara.

Umwanzuro

Ibisubizo byafomate ya potasiyumuKu icyitegererezo cy’indwara yo kuvura inkoko z’inkoko z’inkoko, hagaragajwe ko formate ya potasiyumu ishobora kugabanya igabanuka ry’imikurire y’inkoko z’inkoko mu bihe bimwe na bimwe binyuze mu kongera ibiro by’umubiri no kugabanya impfu, kandi ishobora gukoreshwa nk’inyongera mu kugabanya ubwandu bwa enteritis itera inkoko z’inkoko z’inkoko z’inkoko.