Mu myaka ibarirwa muri za mirongo, aside butyric yakoreshejwe mu nganda zitunganya ibiryo by'amatungo kugira ngo yongere ubuzima bw'amara n'imikorere myiza y'amatungo. Hashyizweho ibisekuru byinshi bishya kugira ngo binoze uburyo ibikomoka ku bimera bifatwa n'imikorere yabyo kuva igeragezwa rya mbere ryakorwa mu myaka ya za 80.

Mu myaka ibarirwa muri za mirongo, aside butyric yakoreshejwe mu nganda zitunganya ibiryo by'amatungo kugira ngo yongere ubuzima bw'amara n'imikorere myiza y'amatungo. Hashyizweho ibisekuru byinshi bishya kugira ngo binoze uburyo ibikomoka ku bimera bifatwa n'imikorere yabyo kuva igeragezwa rya mbere ryakorwa mu myaka ya za 80.

1 Iterambere rya aside butyric nk'inyongera ku biryo

Mu myaka ya 1980 > Aside Butiriki yakoreshejwe mu kunoza iterambere ry'imyakura
Mu myaka ya 1990> umunyu wa aside butyrin wakoreshejwe mu kunoza imikorere y'inyamaswa
Mu myaka ya za 2000> habayeho imyunyu ngugu: amara aboneka neza kandi impumuro yayo ni nkeya
2010> Hashyizweho aside butiriki nshya kandi ikora neza kurushaho

Muri iki gihe isoko ryiganjemo aside butyric irinzwe neza. Abakora ibiryo by’inyongeramusaruro bakorana n’ibi biryo nta kibazo bafite ku bibazo by’impumuro kandi ingaruka z’ibi biryo ku buzima bw’amara no ku mikorere yabyo ni nziza kurushaho. Ikibazo ku bicuruzwa bisanzwe bitwikiriwe ni uko aside butyric iba nkeya. Umunyu utwikiriwe ubusanzwe urimo aside butyric iri hagati ya 25-30%, ikaba ari nke cyane.

Iterambere riheruka mu biryo by’inyongera bishingiye kuri aside butyric ni iterambere rya ProPhorce™ SR: esters za glycerol za aside butyric. Izi triglycerides za aside butyric zishobora kuboneka mu mata no mu buki. Ni zo soko nziza cyane ya aside butyric irinzwe ifite igipimo cya aside butyric kugeza kuri 85%. Glycerol ifite umwanya wo kugira molekile eshatu za aside butyric zifatanye nayo binyuze mu byitwa 'ester bonds'. Izi sano zikomeye ziboneka muri triglycerides zose kandi zishobora kuvunika gusa na enzymes runaka (lipase). Mu gifu no mu gifu, tributyrin iguma mu buryo bwuzuye kandi mu mara aho pancreas lipase iboneka byoroshye, aside butyric irarekurwa.

Uburyo bwo gupima aside butyric bwagaragaye ko ari bwo buryo bwiza cyane bwo gukora aside butyric idafite impumuro isohoka aho uyishakiye: mu mara. Itandukaniro riri hagati y’imyunyu yasizwe rigaragara ku ishusho ya 2.

Mu isuzuma rya 20 rya ESPN i Prague, hagaragajwe ubushakashatsi ku ngaruka z’inyongera ebyiri zitandukanye zishingiye kuri aside butyric mu nyamaswa z’inkoko. Igerageza ryakorewe mu kigo cy’ubushakashatsi cya ADAS mu Bwongereza mu 2014. Bagereranije umunyu wa sodium (ufite 68% by’ipfundikizo) na ProPhorce™ SR 130 (55% by’ipfundikizo butyric). Imishwi 720 ya Coss308 y’ingabo yagabanyijwemo amatsinda 3, hamwe n’ibiraro 12 by’inyoni 20 kuri buri tsinda. Kugira ngo bigane imiterere y’ubucuruzi uko bishoboka kose, hongewemo imyanda yanduye nyuma yo gusuzuma indwara za parasitology, bagiteri na virusi.

Imikorere ya Tributyrin

1.Isana inzoka nto z'amatungo kandi ikabuza bagiteri zangiza amara.

2.Inoza uburyo intungamubiri zifashishwa mu gufata no kuzikoresha neza.

3. Bishobora kugabanya impiswi n'umunaniro wo konka ku matungo magufi.

4. Yongera umuvuduko wo kubaho no kwiyongera ibiro by'amatungo magufi buri munsi.