Ni izihe ngaruka za acide kama na glyceride acide muri "kurwanya bibujijwe no kugabanya kurwanya"？
Kuva ibihugu by’Uburayi bibuza antibiyotike itera imbere (AGPs) mu 2006, ikoreshwa rya acide kama mu mirire y’inyamaswa ryabaye ingirakamaro mu nganda z’ibiryo. Ingaruka nziza zabo ku bwiza bwibiryo n’imikorere y’inyamaswa zimaze imyaka ibarirwa muri za mirongo, kuko zigenda zikurura inganda z’ibiryo
Acide organic ni iki?
Acide Organic "bivuga acide zose zitwa acide carboxylic yubatswe kuri skeleton ya karubone ishobora guhindura imiterere ya physiologique ya bagiteri, igatera metabolike idasanzwe ikumira ikwirakwizwa kandi iganisha ku rupfu.
Acide hafi ya zose zikoreshwa mu mirire y’inyamaswa (nka acide formique, aside protionique, aside lactique, acide acetike, acide sorbic cyangwa acide citric) ifite imiterere ya alifatique kandi ni isoko yingufu za selile. Ibinyuranye,
acide benzoicyubatswe ku mpeta ya aromatic kandi ifite ibintu bitandukanye byo guhinduranya no kwinjiza.
Kuzuza acide kama kuri dosiye ikwiye cyane mubiryo byamatungo birashobora kongera uburemere bwumubiri, kunoza ibiryo no kugabanya ubukoroni bwa virusi mu mara.
1, gabanya agaciro ka pH nubushobozi bwo kugaburira ibiryo kimwe ningaruka za antibacterial na antifungal.
2, mukurekura hydrogene ion mu gifu kugirango igabanye agaciro ka pH, bityo igakora pepsinogen kugirango ikore pepsin kandi itezimbere igogorwa rya poroteyine;
3. Kubuza bagiteri-mbi ya bagiteri mu nzira ya gastrointestinal.
4, metabolite hagati - ikoreshwa nkingufu.
Imikorere ya acide organic mukubuza gukura kwa mikorobe biterwa nagaciro kayo ka pKa, isobanura pH ya acide kuri 50% muburyo bwayo butandukanijwe kandi butavangiye. Iheruka nuburyo acide organic ifite imiti igabanya ubukana. Iyo acide organic iba muburyo butavangiye niho ishobora kunyura murukuta rwa bagiteri na fungi hanyuma igahindura metabolism yabo iba ifite ubushobozi bwa mikorobe. Rero, ibi bivuze ko anticicrobial efficacy ya acide organic iba myinshi mugihe cya acide (nko mu gifu) kandi ikagabanuka kuri pH itabogamye (mu mara).
Kubwibyo, acide organic ifite agaciro gakomeye ka pKa ni acide nkeya hamwe na mikorobe ikora neza mugaburo bitewe numubare munini wimiterere idahwitse igaragara mubiryo, bishobora kurinda ibiryo ibihumyo na mikorobe.
Gliseride
Mu myaka ya za 1980, umuhanga w’umunyamerika Agre yavumbuye proteine selile yitwa aquaporin. Ivumburwa ry'imiyoboro y'amazi rifungura agace gashya k'ubushakashatsi. Kugeza ubu, abahanga basanze aquaporine ibaho cyane mu nyamaswa, ibimera na mikorobe.
Binyuze muri synthesis ya acide propionic na acide butyric na glycerol, α-monopropionic acide glycerol ester, α-monobutyric acide glycerol ester, muguhagarika bagiteri na umuyoboro wa glycerol, bibangamira uburinganire bwingufu zabo hamwe nuburinganire bwimikorere ya membrane, kugirango babuze inkomoko yingufu, kugirango babuze ingaruka nziza za bagiteri.
Agaciro ka pKa ya acide kama ningaruka zazo zo kubuza mikorobe. Igikorwa cya acide kama mubisanzwe biterwa na dose, kandi nibindi byinshi bikora bigera kurubuga rwibikorwa, niko ibikorwa bisabwa. Ibi ni ingirakamaro haba mu kubungabunga ibiryo ndetse no ku mirire no ku buzima ku nyamaswa. Niba acide zikomeye zihari, umunyu wa acide kama urashobora gufasha kugabanya ubushobozi bwo kugaburira ibiryo kandi birashobora gutanga anion kubyara aside irike.
Glyceride ya acide ifite imiterere yihariye, α-monopropionate na α-monobutyric glyceride, igira ingaruka zidasanzwe za bagiteri zica kuri Salmonella, Escherichia coli nizindi bagiteri zitari nziza na clostridium muguhagarika umuyoboro wamazi wa glycerine ya bagiteri, kandi izo ngaruka ziterwa na bagiteri ntizigarukira ku gaciro ka pKa nagaciro ka PH; Ntabwo igira uruhare mu mara gusa, ahubwo inagira aside irike ya acide glyceride yinjizwa mu maraso binyuze mu mara, kandi igera mu bice bitandukanye byanduye umubiri binyuze mu mitsi kugira ngo irinde kandi irinde kwandura virusi.
Igihe cyo kohereza: Kanama-22-2024 
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